Defective memory engram reactivation underlies impaired fear memory recall in Fragile X syndrome
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چکیده
منابع مشابه
Cortisol and Working Memory In Boys With Fragile X Syndrome
Shinkareva for their feedback and support throughout this process. iv ABSTRACT Fragile X Syndrome (FXS) is a neurodevelopmental disorder and the most common cause of inherited intellectual disability. Although FXS is associated with global cognitive impairments, specific deficits in working memory have been reported in young males with FXS. Working memory is an important cognitive process that ...
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A comparative framework of memory processes in males with fragile X syndrome (FXS) and Typically Developing (TYP) mental age-match children is presented. Results indicate a divergence in sequencing skills, such that males with FXS recall sequences similarly to TYP children around five and a half years of age, but eth males with FXS recall significantly worse when compared to TYP children around...
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Although it is believed that different types of memories are localized in discreet regions of the brain, concrete experimental evidence of the existence of such engrams is often elusive. Despite being one of the best characterized memory systems of the brain, the question of where fear memories are localized in the brain remains a hotly debated issue. Here, we combine site-specific behavioral p...
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ژورنال
عنوان ژورنال: eLife
سال: 2020
ISSN: 2050-084X
DOI: 10.7554/elife.61882